New molecular mechanism of C9orf72 mutation linked to amyotrophic lateral sclerosis and frontotemporal dementia

  • 9.February, 2024
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Researchers from the team led by Prof. Dr. Boris Rogelj, along with young researcher Urša Čerček and former colleague Dr. Mirjana Malnar, have published a study in the prestigious journal Nature Communications unveiling novel molecular mechanisms associated with the mutation in the C9orf72 gene, implicated in the development of Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal […]

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Glycosylation profiles of cystatin F alter the cytotoxic potential of NK cells

  • 9.February, 2024
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Colleagues at B3 Emanuela Senjor, Milica Perišić Nanut, Jerica Sabotič and Janko Kos published an article entitled “Different glycosylation profiles of cystatin F alter the cytotoxic potential of natural killer cells” in the journal Cellular and Molecular Life Sciences. The article shows that changing the N-glycosylation of cystatin F significantly affects its localization (within cytotoxic […]

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A review exploring the mechanisms of Campylobacter jejuni adhesion

  • 9.February, 2024
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Jerica Sabotič and Nika Janež, in collaboration with Anja Klančnik from the Biotechnical faculty at University of Ljubljana, have recently published a review paper entitled »Molecular structures mediating adhesion of Campylobacter jejuni to abiotic and biotic surfaces”, which provides a comprehensive overview of the molecular and functional aspects of adhesion of C. jejuni, which is […]

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Research into fungal proteins for safer pest control

  • 9.February, 2024
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As certain soil insects, such as the destructive larvae of the western corn rootworm, are becoming increasingly difficult to control due to insecticide bans, our department is looking for alternative solutions. Investigating fungal proteins as potential biological insecticides, we focused on protease inhibitors, which are known to interfere with insect digestion. In collaboration with partners […]

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New ARIS projects at the department

  • 12.November, 2023
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At this year’s project proposal call from national research agency ARIS postdoctoral project from colleague Emanuela Senjor was selected for two-year financing. Additionally, also few project from our collaborative partners have been selected for financing.

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Department at SBD congress

  • 10.November, 2023
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Members of the department at congress of Slovenian biochemical society (SBD) in Portorož this September that we attended in larger number. At the congress we were very active and presented our work as oral presentations or as posters. The congress was also an excellent opportunity for networking and connecting with other researchers in the field […]

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Cathepsin inhibitors nitroxoline and its derivatives inhibit SARS-CoV-2 infection

  • 25.August, 2023
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Colleagues Ana Mitrović and Janko Kos from department in collaboration with colleges from Faculty of Pharmacy, University of Ljubljana and ICGEB in Trieste published the paper in journal Antiviral Research (IF = 10.103) entitled »Cathepsin inhibitors nitroxoline and its derivatives inhibit SARS-CoV-2 infection«. In paper the authors demonstrated that selective cathepsin B inhibitors, such as […]

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Change in FUS protein involved in early onset of FTD

  • 25.April, 2023
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Researchers from the department prof. dr. Boris Rogelj, assist. prof. dr. Helena Motaln and young researcher Urša Čerček, together with colleagues from Germany and the Netherlands discovered change in FUS protein involved in early onset of frontotemporal dementia (FTD). By synthesizing and validating a specific detector (antibody) for the modified last amino acid of FUS […]

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NMR in microbial glycobiology

  • 20.January, 2023
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Join us at the mini-symposium on NMR in microbial glycobiology, which will be held on Tuesday, January 24, 2023, at 10:00 a.m at the Jozef Stefan Institute, in the main Institute lecture hall, Jamova cesta 39, Ljubljana. We organize this event together with prof. Anja Klančnik from Biotehnical Faculty. Nuclear magnetic resonance (NMR) is a […]

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Excellent in Science 2022

  • 20.December, 2022
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Among the research achievements that were included in the Excellent in Science 2022 selection, which is carried out by the Slovenian Research Agency as part of the promotion of science, there are also articles by colleagues from the department.Among the 21 research achievements that were also selected for public presentation is the achievement of prof. […]

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