L’Oreal-UNESCO “For Women in Science” recipient

  • 4.April, 2024
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Urša Čerček from our department became the recipient of 2024 National Program for Women in Science, which promotes and supports research projects of female scientists in Slovenia. She has been awarded for her work in the field of biochemistry and molecular biology of neurodegenerative diseases.Urša joins 49 previous scholarship recipients under the L’Oreal-UNESCO “For Women […]

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Improving biodiscovery with the guide to the use of bioassays

  • 20.February, 2024
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Jerica Sabotič and Nika Janež from the Department of Biotechnology of the Jožef Stefan Institute, in collaboration with blue biotechnology experts who are members of the COST Action Network CA18238 Ocean4Biotech, have prepared a comprehensive guide for the use of bioassays for effective discovery of bioactive compounds, which has been published in the prestigious journal […]

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New substrate for laccase activity assays

  • 20.February, 2024
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The group of Inga Matijošyte from Life Sciences Center at the Institute of Biotechnology of Vilnius University in Vilnius, Lithuania, has developed a new substrate for the detection of laccase activity, Ferbamine. Laccases are versatile enzymes that catalyze oxidation reactions coupled to the reduction of molecular oxygen to water. They enable the degradation of lignin, […]

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New molecular mechanism of C9orf72 mutation linked to amyotrophic lateral sclerosis and frontotemporal dementia

  • 9.February, 2024
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Researchers from the team led by Prof. Dr. Boris Rogelj, along with young researcher Urša Čerček and former colleague Dr. Mirjana Malnar, have published a study in the prestigious journal Nature Communications unveiling novel molecular mechanisms associated with the mutation in the C9orf72 gene, implicated in the development of Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal […]

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Glycosylation profiles of cystatin F alter the cytotoxic potential of NK cells

  • 9.February, 2024
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Colleagues at B3 Emanuela Senjor, Milica Perišić Nanut, Jerica Sabotič and Janko Kos published an article entitled “Different glycosylation profiles of cystatin F alter the cytotoxic potential of natural killer cells” in the journal Cellular and Molecular Life Sciences. The article shows that changing the N-glycosylation of cystatin F significantly affects its localization (within cytotoxic […]

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A review exploring the mechanisms of Campylobacter jejuni adhesion

  • 9.February, 2024
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Jerica Sabotič and Nika Janež, in collaboration with Anja Klančnik from the Biotechnical faculty at University of Ljubljana, have recently published a review paper entitled »Molecular structures mediating adhesion of Campylobacter jejuni to abiotic and biotic surfaces”, which provides a comprehensive overview of the molecular and functional aspects of adhesion of C. jejuni, which is […]

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Research into fungal proteins for safer pest control

  • 9.February, 2024
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As certain soil insects, such as the destructive larvae of the western corn rootworm, are becoming increasingly difficult to control due to insecticide bans, our department is looking for alternative solutions. Investigating fungal proteins as potential biological insecticides, we focused on protease inhibitors, which are known to interfere with insect digestion. In collaboration with partners […]

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New ARIS projects at the department

  • 12.November, 2023
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At this year’s project proposal call from national research agency ARIS postdoctoral project from colleague Emanuela Senjor was selected for two-year financing. Additionally, also few project from our collaborative partners have been selected for financing.

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Department at SBD congress

  • 10.November, 2023
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Members of the department at congress of Slovenian biochemical society (SBD) in Portorož this September that we attended in larger number. At the congress we were very active and presented our work as oral presentations or as posters. The congress was also an excellent opportunity for networking and connecting with other researchers in the field […]

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Cathepsin inhibitors nitroxoline and its derivatives inhibit SARS-CoV-2 infection

  • 25.August, 2023
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Colleagues Ana Mitrović and Janko Kos from department in collaboration with colleges from Faculty of Pharmacy, University of Ljubljana and ICGEB in Trieste published the paper in journal Antiviral Research (IF = 10.103) entitled »Cathepsin inhibitors nitroxoline and its derivatives inhibit SARS-CoV-2 infection«. In paper the authors demonstrated that selective cathepsin B inhibitors, such as […]

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