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A Biosafety Level 2 (BSL2) laboratory has been established in the Department of Biotechnology for for simultaneous work with bacteria and eukaryotic cell lines enabling interdisciplinary research in the field of microbiology and cell biology. The facilities, equipment and materials are currently being used for the analysis of bacteria-host interactions, bacterial glycobiology and biofilm research […]

At this year’s project proposal call from national research agency ARRS projects form our colleagues Boris Rogej and Ana Mitrović were selected for three-year financing. Additionally, also few project from our collaborative partners have been selected for financing.

On Monday, September 20, 2021, our colleague Tina Vida Plavec received the title PhD with a successful defence of her doctoral dissertation entitled »Surface display of tumor antigen binders on Lactococcus lactis NZ9000 and evaluation of their binding to selected human tumor cell lines«. She conducted her research work at the department, under the mentorship […]

Janja Božič, Helena Motaln, Anja Pucer Janež and Lara Markič headed by prof. dr. Boris Rogelj and in collaboration with researchers from Germany, the Netherlands and the United Kingdom, identified protein interactions of factors that can cause neurodegenerative diseases such as frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) if they accumulate in the wrong […]

A paper »Targeting of fluorescent Lactococcus lactis to colorectal cancer cells through surface display of tumour-antigen binding proteins« was published in Microbial Biotechnology by members of the department Tina Vida Plavec, Ana Mitrović, Milica Perišić Nanut, Borut Štrukelj, Janko Kos and Aleš Berlec. Safe multifunctional cancer cell targeting bacteria Lactococcus lactis were developed to target […]

Members of Department Emanuela Senjor, Milica Perišić Nanut, Ana Mitrović and Janko Kos recently published a paper entitled: Cystatin F acts as a mediator of immune suppression in glioblastoma in Cellular Oncology ( IF = 6,73). The paper shows that elevated cystatin F levels in glioblastoma tumor microenvironment (from immune, glioblastoma, or glioblastoma stem-like cells) […]

Between 3rd and 8th July 2021, a virtual congress of the Federation of European Biochemical Societies (FEBS) entitled Molecules of Life: Towards New Horizons was held. The congress was originally supposed to be organized in Ljubljana, however despite the virtual implementation, it retained a strong Slovenian touch. It was attended by more than 1,700 participants […]

Prof. Rogelj in collaboration with colleagues from King’s College London published a review article on disease relevance of nucleocytoplasmic shuttling in the esteemed journal Brain (IF 13.5). Abnormalities in expression and function of proteins that are involved in nucleocytoplasmic shuttling called karyopherins can be both the cause and consequence of protein mislocalisation and aggregate formation […]

On Thursday, May 6, 2021, our colleague Mirjana Malnar received the title PhD with a successful defence of her doctoral dissertation entitled »Role of antisense RNA transcript from C9orf72 mutation associated with amyotrophic lateral sclerosis and frontotemporal dementia«. She conducted her research work at the department, under the mentorship of prof. Boris Rogelj. Congratulations!

Prof. Boris Rogelj and Miha Milek from the Institute of Chemistry on Radio Student spoke about major breakthroughs in cell and molecular biology in recent decades, especially in terms of research in the field of RNA molecules and the role of non-coding RNA in regulating gene expression. You can listen to the article at the […]