Yearly Archives: 2022

This year we successfully purchase new flow cytometer Attune™ NxT Flow Cytometer with four lasers (blue, red, violet and yellow), autosampler, and additional filter for detection of small particle down to 100 nm. The cytometer uses the combination of innovative acoustic focusing technology coupled with traditional hydrodynamic focusing that enables its high acquisition speeds. New […]

Members of the Department Abida Zahirović and Aleš Berlec have recently published a paper entitled »Targeting IL-6 by engineered Lactococcus lactis via surface-displayed affibody« in Microbial Cell Factories (IF = 6.35). They developed lactic acid bacteria Lactococcus lactis with potent and selective IL-6 binding activity by displaying IL-6-specific affibody on its surface. Engineered bacteria were […]

Based on our description of a new family of fungal peptidase inhibitors, Cocaprins, a new Merops family I106 was established. Members of our department Jerica Sabotič, Tanja Zupan, Milica Perišić Nanut and Janko Kos worked on the biochemical characterization in collaboration with Miha Renko and Dušan Turk from the Department of Biochemistry and Molecular Biology, […]

Our laboratories are now richer for two microscopes equipped with cameras that can capture high-resolution images. The first is the EVOS M5000 Imaging System, which allows observation of cells in brightfield at various magnifications, as well as capturing a wide range of fluorescence monitoring in four different channels. The second microscope is the Olympus CKX53, […]

A paper entitled »Dual Functionalized Lactococcus lactis Shows Tumor Antigen Targeting and Cytokine Binding in Vitro« (IF = 6.06) was published by the members of the Department Abida Zahirović, Tina Vida Plavec and Aleš Berlec in the Frontiers in Bioengineering and Biotechnology. Lactococcus lactis bacteria with dual functionality were developed by displaying two distinct bioactive […]

Emanuela Senjor received Faculty of Pharmacy Deans’ Award 2021 awarded yearly for best research work in the past year published in research journals ranked top 10% among journals of specific research field. She received the award for her research study Cystatin F acts as a mediator of immune suppression in glioblastoma, published in Cellular Oncology.

New cell wall teichoic acid (WTA) from Listeria innocua ŽM39 was characterized including the analysis of its biosynthesis genes by members of Department Nika Janež and Jerica Sabotič in collaboration with Anja Klančnik and Meta Sterniša from Biotechnical faculty, University of Ljubljana, with Barbara Bellich, Paola Cescutti and Roberto Rizzo from University of Trieste, and […]

You can simultaneously test antimicrobial and antibiofilm activity against Salmonella by analysing their growth curve. Jerica Sabotič, in collaboration with Meta Sterniša and Anja Klančnik from the Biotechnical Faculty of the University of Ljubljana, described this simple approach in the International Journal of Food Microbiology and filed a patent application.This simple approach, called Simba, was […]

Members of department Ana Mitrović and Janko Kos with coworkers’ form Department of Biochemistry and Molecular Biology and coworkers from Faculty of Pharmacy, University of Ljubljana published the paper in journal Cellular and Molecular Life Science (IF = 9.261) entitled “Evaluation of novel cathepsin-X inhibitors in vitro and in vivo and their ability to improve […]

On 1 January 2022, we started our work under a new research programme entitled Marine and Microbial Biotechnology, led by Dr Ana Rotter from the National Institute of Biology and in collaboration with Prof Nina Gunde Cimerman from the Biotechnical Faculty at the University of Ljubljana. The research programme focuses on marine and related extreme […]