New WTA structure in Listeria

• Post by: Ana Mitrović
• 19.January, 2022
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New cell wall teichoic acid (WTA) from Listeria innocua ŽM39 was characterized including the analysis of its biosynthesis genes by members of Department Nika Janež and Jerica Sabotič in collaboration with Anja Klančnik and Meta Sterniša from Biotechnical faculty, University of Ljubljana, with Barbara Bellich, Paola Cescutti and Roberto Rizzo from University of Trieste, and with Neil Ravenscroft from University of CapeTown. Rigorous NMR analysis performed at University of Trieste showed a new type II WTA structure in Listeria similar to serovar 6a with disaccharide αGlcNAc-(1-3)-βGlcNAc linked to C4 of Ribitol. Moreover, Nika Janež annotated the newly sequenced genome of the strain, which allowed identification of putative WTA biosynthesis genes.

Link: https://doi.org/10.1016/j.carres.2021.108499