Internalisation of extracellular cystatin F by cytotoxic T lymphocytes

• Post by: Ana Mitrović
• 18.December, 2020
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Reputable journal Cancers (IF 6.64) published a paper by members of the department Mateja Prunk, Milica Perišić Nanut, Jerica Sabotič and Janko Kos entitled “Extracellular Cystatin F Is Internalised by Cytotoxic T Lymphocytes and Decreases Their Cytotoxicity”. The article demonstrates that extracellular cystatin F after internalisation into cytotoxic T cells decreases their killing ability by affecting the activation of granzymes, effector molecules crucial for target cell killing. The open access article can be accessed at https://www.mdpi.com/2072-6694/12/12/3660?type=check_update&version=1.