New antibacterials identified in mushrooms

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• 2.June, 2020
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In the search for new antibacterial proteins from mushrooms, members of the Department of Biotechnology Jerica Sabotič, Jože Brzin and Janko Kos in collaboration with researchers from the National Institute of Biology discovered that L-amino acid oxidases (LAO) with strong antibacterial activity are present in mushrooms. These enzymes are otherwise known as an important component of snake venom. The results were published in the article L-Amino Acid Oxidases From Mushrooms Show Antibacterial Activity Against the Phytopathogen Ralstonia solanacearum (doi: 10.3389/fmicb.2020.00977). These fungal LAO represent a new potential biological phytoprotective agent and show mushrooms to be a rich source of antimicrobial substances with unique properties.